POLYPHIL - PHILART - CROMA

🧬 POLYPHIL (formerly PhilArt) from Croma-Pharma: The New Name for Polynucleotides

🌟 Croma-Pharma & POLYPHIL: Innovation in Tissue Biostimulation

Croma-Pharma GmbH is a leading Austrian laboratory with expertise in hyaluronic acid (HA) fillers (Saypha) and tissue regeneration solutions. The POLYPHIL brand (formerly marketed as PhilArt or sometimes referred to as Nucleofill in similar technologies) represents this new generation of injectable products. POLYPHIL is an injectable medical device designed to improve skin quality, cell regeneration, and firmness through the use of polynucleotides (PN). The principle of biostimulation for PN/PND Unlike hyaluronic acid, which provides volume and hydration, PN/PND act as biostimulators: It creates an environment conducive to cell regeneration. It hydrates the extracellular matrix. It stimulates the production of collagen and elastin by fibroblasts.

🔬 POLYPHIL Technology: Polynucleotides Natural

The products in the POLYPHIL range are composed of naturally derived polynucleotides (from fish DNA), highly purified and sterile.

• Tissue Action: The polynucleotides act directly on the skin's structure, improving its elasticity, firmness, and radiance.
• Antioxidant Protection: The polynucleotides neutralize free radicals, thus contributing to the overall skin process.
• Bio-Integration: The product integrates with textiles, acting as a biomimetic for regeneration.

🗺️ The POLYPHIL Range: Solutions for the Face, Eyes, and Neck

The POLYPHIL range offers different concentrations adapted to specific areas of delicacy or fineness:

• POLYPHIL (standard. Face, Neck, Décolleté. Concentration possible. General revitalization, firmness, texture.
• POLYPHIL Eye Zone Peri-ocular. Low concentration. Treatment of fine lines around the eyes and dark circles.
• POLYPHIL Forte. Body, Scalp. High concentration. Rejuvenation of hands and body, and scalp densification.

❓ FAQ on POLYPHIL

Q: What is the main function of the polynucleotides (PN) in POLYPHIL? A: Their main function is biostimulation and tissue regeneration. PN hydrates the dermis, improves the extracellular matrix, and stimulates fibroblasts to produce new collagen and elastin fibers.

Q: Is the POLYPHIL treatment painful? A: PN injections are generally well tolerated. Very fine needles or cannulas can be used. A local anesthetic cream can be applied before the session to optimize patient comfort.

Q: Is it recommended to combine several POLYPHIL sessions for optimal results? A: The protocol varies depending on the individual situation and skin performance, generally requiring 3 to 4 sessions, spaced 2 to 4 hours apart. weeks, and a maintenance session every 6 to 9 months.

Q: Can POLYPHIL be combined with Hyaluronic Acid (HA) filler? A: Yes, the two treatments are very complementary. HA (Saypha) provides immediate volume and hydration, while POLYPHIL improves the skin's intrinsic quality and long-term firmness.

Q: Is there any downtime after a POLYPHIL session? A: Downtime is minimal. Slight redness, swelling, or small bruises may occur at the injection site, generally disappearing within 24 to 48 hours.

POLYPHIL RANGE

POLYPHIL PhilArt

• Composition: PN-HPT 40 mg/2 ml
• Packaging: 1 x 2 ml syringe
• Needle: 2 x 30G 1/2, 13 mm
• Suggested indications: young skin – neck, forehead, hands, scars, acne scars
• Injection depth: Intradermal
• Injection technique: microdroplets, linear or fanned (needle)

POLYPHIL PhilArt eye

• Composition: PN-HPT 15 mg/2 ml.
• Packaging: 1 x 2 ml syringe.
• Needle: 2 x 30G 1/2, 13 mm.
• Suggested indications: eye contour, eyelids.
• Injection depth: Intradermal.
• Injection technique: microdroplets, linear or fanned (needle).

POLYPHIL PhilArt hair

• Composition: PN-HPT 15 mg/2 ml.
• Packaging: 1 x 2 ml syringe.
• Needle: 2 x 30G 1/2, 13 mm.
• Suggested indications: hair, eyebrows.
• Injection depth: Intradermal.
• Injection technique: microdroplets or linear (needle).

POLYPHIL PhilArt next

• Composition: PN-HPT 20 mg/2 ml. Hyaluronic acid 20 mg/2 ml.
• Packaging: 1 x 2 ml syringe.
• Needle: 2 x 30G 1/2, 13 mm.
• Suggested indications: Mature and dehydrated skin – face, mid-face, scars, acne scars.
• Depth: Intradermal
• Injection technique: Microdroplets, linear or fanning technique (needle).