NUCLEOFILL 20 MEDIUM (1x1,5ml)
NUCLEOFILL Medium offers a multiplied and long-lasting rejuvenating effect. The concentrated polynucleotides in this product effectively activate cell renewal in a lasting and preventative way. Collagen and elastin production is stimulated, leading to skin thickening and lifting.
NUCLEOFILL20 MEDIUM (1 x 1.5 ml)
Important Note: STRICTLY FOR MEDICAL USE. This medical device must be administered only by a qualified healthcare professional.
Nucleofill Strong (20) is a major innovation in aesthetic medicine, developed by the Promoitalia laboratory. It is not simply a filler, but a deep bio-restructuring treatment formulated with high molecular weight polynucleotides.
Nucleofill Medium offers a multiplied and long-lasting rejuvenating effect. The concentrated polynucleotides in this product effectively activate cell renewal in a lasting and preventative way. Collagen and elastin production is stimulated, leading to skin thickening and lifting. This product creates a powerful antioxidant effect. The skin gains deep hydration and firmness. This product is indicated for skin exposed to stress, oxygen deficiency, dehydrated skin, stretch marks, and scars.
Why choose Nucleofill 20 Medium?
The laboratory's approach is based on three fundamental actions for the skin:
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Lifting Effect (Tissue Gymnastics): Stimulation of CD39 and CD40 receptors on fibroblasts to redensify the skin matrix.
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Antioxidant Action: Powerful neutralization of free radicals (scavenger effect) to stop oxidative stress.
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Iso-osmotic Hydration: Polynucleotides retain water, ensuring long-lasting hydration of the matrix extracellular.
Technical Characteristics
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Brand: Promoitalia
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Range: Nucleofill
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Version: Strong (High Viscosity)
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Polynucleotide concentration: 2% (20mg/ml)
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pH: 6.8 and 7.2
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Viscosity: 428 -43 pa*s
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Packaging: 1 x 1.5 ml syringe
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Needles included: 2 x 30G 13mm needles included in each box
Indications and Targeted Areas
Nucleofill 25 is specifically formulated for skin exposed to oxidative stress, dehydrated, or showing a loss of firmness.
Ideal for treating:
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Moderate to severe skin laxity.
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Deep wrinkles and fine lines.
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Dehydrated and Dull.
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Lack of firmness (liquid lifting effect).
Recommended application areas:
Nucleofill is suitable for all skin types, regardless of maturity:
- Wrinkles & Skin wrinkles
- Skin aging
- Skin exposed to oxidative stress (pollution, sun, tobacco, lifestyle)
- Dehydrated skin
- Before injections, to prolong their aesthetic effects
- Stretch marks
- Scars
Instructions for Use
Important Note: This medical device must be administered only by a qualified healthcare professional.
Promoitalia Laboratories suggests specific injection techniques to maximize bio-restructuring, including:
The 5-Point Technique (Bio-points) Linear or fan-shaped technique
🌟 Benefits
✅ Natural origin: Highly purified polynucleotides.
✅ Safety: High viscoelasticity and total biocompatibility.
✅ Results: Visibly improved skin quality, firmness, and radiance without altering natural facial features.
❓ Frequently Asked Questions (FAQ)
What is the difference between Nucleofill Medium and Nucleofill Strong (25)? Nucleofill Strong (25) contains a higher concentration of polynucleotides (25mg/ml) compared to Medium (20mg/ml). It is therefore preferred for more mature, thicker skin or skin requiring a more pronounced lifting effect.
Is Nucleofill hyaluronic acid? No. Although it hydrates, Nucleofill is a polynucleotide gel. Unlike hyaluronic acid, which fills mechanically (volumizer), Nucleofill stimulates the skin's biological regeneration (biostimulator).
How long do the effects last? The results are long-lasting thanks to tissue regeneration. However, as with any biostimulator, the duration depends on the patient's age, skin type, and lifestyle. Maintenance sessions are recommended by the manufacturer.